'Nati Binodini' is the biopic of Binodini a girl born into prostitution but who became famous in Bengal as theatre actress. She is brought into theatre by Girish Ghosh and makes name for herself. Her struggles, her eminent role in the formation of Star Theatre and her sacrifices for the same are shown. She was a pioneering entrepreneur of Bengali stage. Her meeting with Sri Ramkrishna Dev, his liking for her acting and his blessings change her life significantly. She gives up acting which was her life after the sudden demise of the lord.